Vol 3 Issue 5 September 2016-October 2016
Garba, I., Umar, A.I., Nuhu, A., Tijjani, M.B., Aliyu, M.S., Salisu, H., Unata, I.M
Abstract: Diarrheal disease is a global public health problem causing considerable morbidity and mortality among infants and children especially in the developing countries. Acute diarrhea due to Escherichia coli infections is an important cause of Morbidity and mortality in infants and young children in most developing countries including Nigeria. The aim of the study was to determine the prevalence and antibiogram of Escherichia coli among children (<1ss-5years) with diarrhea in some selected hospital in Sokoto metropolis. A total of 150 stool samples of children with diarrheal disease were collected (75) from Sokoto Specialist Hospital, (75) from Maryam Abacha Women and Children Hospital Sokoto. Antimicrobial Susceptibility Testing was carried out and diameter of zone of inhibition measured following standard microbiological techniques. Out of the 150 samples analysed, ninety seven (64.7%) yielded growth of Escherichia coli. Of the 75 samples collected from Specialist Hospital Sokoto 52 (69.3%) yielded growth of Escherichia coli, a total of 75 samples were collected from Maryam Abacha and analysed, 45(60%) showed growth of Escherichia coli. The prevalence of Escherichia coli among males was (30.93%) while a high prevalence of 69.07% was observed in female children. The highest prevalence of 46.6% was observed in children aged 2-3 years. While the lowest prevalence 10.3% was seen in the age group 3-4 in years. Children aged <1 year had 16.5% prevalence rate, while age group 1-2 years had a prevalence of 11.3% in contrast to children aged 4-5 years that had a prevalence of 15.5%. The highest susceptibility to Nitrofurantoin 95% was observed followed by norfloxacin 92%. The susceptibility to ciprofloxacin and augmentin were 82% and 72% respectively. Intermediate susceptibilities were observed in respect of chloramphenicol 30% and tetracycline 20%, highest resistant to amoxicillin 100% was observed followed by erythromycin 90%, tetracycline 72% and chloramphenicol 60%. Few isolates were resistant to Norfloxacin 8% and Nitrofurantoin 5%. E. coli remains one of the major cause of diarrhea among diarrheagenic children in the selected study hospitals in Sokoto.
Keywords:Prevalence, Escherichia coli, Children, Diarrhea, Sokoto.
Title: PREVALENCE OF ESCHERICHIA COLI AMONG CHILDREN (<1-5Yrs) WITH DIARRHEA IN SELECTED HOSPITALS IN SOKOTO METROPOLIS
Author: Garba, I., Umar, A.I., Nuhu, A., Tijjani, M.B., Aliyu, M.S., Salisu, H., Unata, I.M
International Journal of Novel Research in Life Sciences
ISSN 2394-966X
Novelty Journals