Vol 11 Issue 2 September 2024-February 2025
Nwogbu Celestine Chidi, Udeh Ubasinachi Osmond, Nwogbu Paul Iloabuchi
Abstract: The research study on the anti-bacterial property of beta phase TiCu alloy was handled by antibacterial test on Eschericha Coli(E,C) and Staphylococcus Aureus(S.A) colonies on the specimens. Research studies indicated that the Ti 17%Cu alloy specimen exhibited excellent antibacterial property, providing a great potential in clinical application for gynaecological implants.The research of antimicrobial/antibiofilm activities of the beta phase contraceptive Titanium Copper alloy (TiCu) against these bacterial species showed an excellent antibacterial effect in vitro, thus inhibiting both Escherichia coli and Staphylococcus Aureus. This research innovated the design and production of Beta((β) phase TiCu alloy specimens in the categories of ; Ti0.5%Cu, Ti1.0%Cu, Ti2.0%Cu, Ti5.0%Cu, Ti10.0.0%Cu, Ti15.0%Cu and Ti17.0% Cu, using Copper element as the experimental control reference biomaterial. The TiCu alloy specimens were produced by powder metallurgy technique in an inert environment. Experimental investigations and Minitab Software Design analyses on the these specimens for combined antibacterial response in direct improvement of mechanical compatibility (tensile strength, hardness value, fracture toughness,), biocompatibility–cell viability (cytocompatibility), corrosion resistance by Electrochemical Impedance Spectroscopy (EIS), contraceptive response integrity(CRI) and the effect of surface treatment were all carried out in order to establish the suitability of Ti17%Cu alloy as a possible replacement to the existing prototype biomaterial( Cu-T380(IUD).
Keywords: biomaterials, contraceptive, titanium copper alloy, gynaecological, beta phase, specimens, endometrium, Cu T380IUD, intra uterine.
Title: EVALUATION OF ANTIBACTERIAL - MICROBIAL PERFORMANCE OF BETA PHASE TITANIUM COPPER ALLOY FOR INTRAUTERINE GYNAECOLOGICAL APPLICATION
Author: Nwogbu Celestine Chidi, Udeh Ubasinachi Osmond, Nwogbu Paul Iloabuchi
International Journal of Novel Research in Engineering and Science
ISSN 2394-7349
Vol. 11, Issue 2, September 2024 - February 2025
Page No: 44-58
Novelty Journals
Website: www.noveltyjournals.com
Published Date: 01-February-2025